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Techniques to study, work and locally probe adherent cells and tissues at micrometer distances from cell surfaces in “open space” would represent a major advance for the biology of biointerfaces.

To this end, one needs tools for observing, patterning, assaying and stimulating biological interfaces, which can address a range of dimensions and volumes commensurate with the cell. Key is to control the physics and chemistry of these interfaces.

Within the BioProbe framework, we will: