Nadya Ostromohov receives the Best Oral Presentation prize at New Concepts in Biosensing conference

Nadya Ostromohov  received an award for best Oral Presentation at the Batsheva de Rothschild Seminar on New Concepts in Biosensing held in Dead Sea, Israel in February 2017 for her work “Sequential delivery of reagents with minimal dispersion for surface chemistry assays and characterization of biomolecular responses.”

In this talk, NadyDSC_1186a focused on a new method for sequential delivery of reagents to a surface-bound reaction site with minimal dispersion of their interfaces. Sequential delivery of multiple reagents is key in a large number of surface biochemical assays and yet is highly challenging to implement. In this method, segmented flows were used to encapsulate the reagents as droplets, thereby keeping dispersion between reagent plugs confined in a limited volume, and were transmitted to the reaction surface using a custom microfluidic probe head. She demonstrated the measurements of receptor-ligand reaction kinetics and protein response to chemical stimuli. Such a method will be useful for studying the dynamic response of cells and proteins to various stimuli, as well as for highly automated multi-step biological assays.

Nadya also recently reported this work in Lab on a Chip; this article was featured as a cover page.

The Batsheva de Rothschild Seminar are topical conferences attended by a select group of internationally leading scientists.

This work was performed as part of Virtual Vials ITN, a project funded by the EU under the FP7 framework. Nadya is academically affiliated to the Microfluidic Technologies Laboratory of Assistant Professor Moran Bercovici at the Department of Mechanical Engineering, Technion, Israel.

Congratulations Nadya!

GovindNadya Ostromohov receives the Best Oral Presentation prize at New Concepts in Biosensing conference

Hydrodynamic thermal confinement (HTC) work online

Congratulations to julien and ariane.

J. F. Cors, A. Stucki, and G. V. Kaigala, “Hydrodynamic Thermal Confinement: Creating Thermo-Chemical Microenvironments on Surfaces,” Chemical Communications, DOI: 10.1039/C6CC08018A, 2016.

GovindHydrodynamic thermal confinement (HTC) work online

microTAS 2016 in Dublin

20th International Conference on Miniaturized Systems for Chemistry and Life Sciences 9-13 October, 2016, Dublin, Ireland.

Nadya and Aditya made oral presentations:

  • A. Kashyap, J.F. Cors, and G.V. Kaigala, “Spatialyze — statially precise analysis of nucliec acids using local cell lysis with a microfluidic probe,” pp 41-42.
  • N. Ostromohov, M. Bercovici, and G.V. Kaigala, “Delivery of minimally dispensed liquid interfaces for sequential surface chemistry using a microfluidic probe,” pp 85-86.

Federico and Xander presented posters:

  • F. Paratore, T. Zeidman Kalman, T. Rosenfeld, G.V. Kaigala, “Isotachaporesis-based surface immunoassay,” and M. Bercovici, pp. 665-666.
  • X.F. van Kooten, M. Truman-Rosentsvit, G.V. Kaigala, and M. Bercovici, “Focusing analytes from 10 uL into 500 pL: On-chip procesing of large volumes using isotachaphoresis,” pp. 898-8999.


GovindmicroTAS 2016 in Dublin

mm/cm-scale surface interaction and processing

Work on mm and cm scale work is out online; congrats david and all other co-authors.

D.P. Taylor, I. Zeaf, R.D. Lovchik, and G.V. Kaigala, “Centimeter-scale surface interactions using hydrodynamic flow confinements,” Langmuir, DOI: 10.1021/acs.langmuir.6b02983, 2016.

Govindmm/cm-scale surface interaction and processing

JoVE paper on cell patterning is now out

A. Kashyap, J.C. Cors, R.D. Lovchik, and G.V. Kaigala, “Rapid subtractive patterning of live cell layers with a microfluidic probe,” J. Vis. Exp., 115, e54447, 2016.


GovindJoVE paper on cell patterning is now out